Project title, ESR4: Supercontinuum generation in specific windows for versatile OCT investigations and spectroscopic OCT
Aiming towards broadening the usability of optical coherence tomography by adding functional information that can be crucial for medical diagnoses.
Current projects and research areas
- Ultra-wide optical coherence tomography in different wavelengths regions using a supercontinuum source
- Spectroscopic visible-light optical coherence tomography for oxygenation detection
- Different wavelength scanning laser ophthalmoscope (SLO) combined with adaptive optics for spectral analysis of samples
To this date medical doctors try to improve their diagnosis for severe diseases using optical imaging technology, which can be further improved to give more precise results. Our aim is to help developing and improving existing imaging modalities such as optical coherence tomography or scanning laser ophthalmoscope and provide additional, functional information, which will enable the medical staff to diagnose diseases with a higher accuracy.
Many eye diseases can be related to the oxygenation of the back of the eye, by improving the possibility in measuring the oxygen saturation many diseases can be diagnosed earlier and damage can be prevented. This will improve the patient’s life and reduce causes of blindness.
2016 – present
University of Kent
Researcher / PhD student
- Integrating a supercontinuum source in an adaptive optics SLO set-up for different wavelength SLO imaging
2014 – 2016
NKT Photonics A/S
Researcher / PhD student
- Optical coherence tomography combined with supercontinuum source in different wavelength regions
- Spectroscopic optical coherence tomography in near infrared and visible wavelength
2011 – 2014
University of Lübeck, Germany
Masters of Science in Biomedical / Medical Engineering
With focus on: Laser physics and optics
2008 – 2011
University of applied Sciences Bremerhaven, Germany
Bachelor of Engineering in Medical Engineering
With focus on: Computational sciences
- F. Fleischhauer, S. Caujolle, T. Feuchter, R. Rajendram, L. Leick and A. Podoleanu, “Spectroscopic low coherence interferometry using a supercontinuum source and an ultra broadband spectrometer”, SPIE Proceedings Vol. 9697: Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX (2016)
Spectroscopic optical coherence tomography (SOCT) combines the imaging capability of optical coherence tomography with spectroscopic absorption information. SOCT requires a large bandwidth combined with a broadband spectrometer, due to the processing of the measured data, which includes dividing the spectrum in spectral bands. Both, spectral and axial resolution of SOCT depend on the spectral width of each window. A supercontinuum source with its broad spectrum allows a sufficient number of windows combined with a reasonable axial resolution, which depends on the application. Here a SOCT system is used in the visible spectral range from 480 to 730 nm by combining a supercontinuum light source, a Michelson interferometer and a commercial available broadband spectrometer. This wavelength range is chosen because it covers a range of useful absorbers, including that of human proteins. The system is tested with a laser dye rhodamine B for calibration and verification. Rhodamine B has an absorption peak at around 542 nm, which resembles the absorption spectrum of several proteins in the globin group. The results show that the absorption spectrum of rhodamine B can be reconstructed with sufficient accuracy and demonstrate that varying spectroscopic information can be retrieved from different depths.